This course is designed for a wide range of learners seeking a foundation of core principles and practical lessons in health & well-being, including researchers and clinicians pursuing expert preparation for the practice of circadian biology in the classroom, laboratory, hospital, and clinic. This course is targeted for graduate students from all areas, but it also should be of interest to practicing researchers, clinicians or everyone for whom biological rhythms are key factors (e.g. medicine, sports kinetics, pharmacy, psychology, nurning). The content of the course will focus in the basics of biological rhythms and their pratical applications, namely: - Basic concepts of circadian timekeeping; - Molecular, cellular, and neural substrates of circadian clocks; - Circadian rhythm synchronization to the 24-hr day-night cycle; - Circadian regulation of physiology, metabolism, and sleep; - Circadian misalignment and its role in disease symptomatology and etiopathogenesis; - Methods for circadian research in model organisms and human subjects; - Methods and protocols for circadian analysis, from molecular to clinical; - Circadian considerations in medical diagnosis and therapy (chronotherapy); - The future of translational and personalized circadian medicine; - Circadian biology and society